Not to belabor the point but I spent years on Prozac, and it resulted in a lot of frustration when you have an easily orgasmic, cum-slut wife, and you can fuck like a stallion, but not show her the slippery, shiny, stringy proof.
For the last eight months, I've happily allowed my serotonin re-uptake to happen as my own body decides, without the chemical inhibitor. This makes orgasm possible again. Sometimes even multiple times daily, but I don't believe I'll ever come close to the two year anniversary benchmark of eleven ejaculations in a 24 hour period. ELEVEN!
The first time I noticed this "side effect" nonchalantly described in Eli Lilly's insert as "various sexual side effects" wasn't sexual at all. I was on the treadmill at the gym. I had run for 20-25 minutes and wasn't feeling the horizon approaching of a runner's high. 35 minutes, then 40, 45...nothing. I sprinted the equivalent of 200 yards at the end, red-faced sweating, pulse throbbing in my temples. Nothing.
So, re-aligning my brain chemistry to a natural state and balance is a pretty big deal for me.